33299

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 173064..173244 Replicon chromosome
Accession NZ_AP020320
Organism Staphylococcus aureus strain KUH180062

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag F6Y17_RS01115 Protein ID WP_001801861.1
Coordinates 173149..173244 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 173064..173121 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F6Y17_RS01085 168773..168907 + 135 WP_001791797.1 hypothetical protein -
F6Y17_RS01090 169071..170627 + 1557 WP_000028669.1 type I restriction-modification system subunit M -
F6Y17_RS01095 170620..171849 + 1230 WP_000072627.1 restriction endonuclease subunit S -
F6Y17_RS01100 172301..172795 + 495 Protein_175 transposase -
F6Y17_RS01105 172786..172947 + 162 Protein_176 transposase -
F6Y17_RS01110 172925..173026 - 102 WP_001792025.1 hypothetical protein -
- 173064..173121 + 58 - - Antitoxin
F6Y17_RS01115 173149..173244 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
F6Y17_RS01120 173389..174401 + 1013 Protein_179 IS3 family transposase -
F6Y17_RS01125 174599..175171 - 573 WP_000414216.1 hypothetical protein -
F6Y17_RS01130 175272..175613 - 342 WP_000627540.1 DUF3969 family protein -
F6Y17_RS01135 175654..176280 - 627 WP_000669024.1 hypothetical protein -
F6Y17_RS01140 176355..177350 - 996 WP_150030548.1 DUF4352 domain-containing protein -
F6Y17_RS01145 177431..178081 - 651 WP_001838777.1 excalibur calcium-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - selk / hlgA / lukD 146231..178839 32608


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T33299 WP_001801861.1 NZ_AP020320:c173244-173149 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T33299 NZ_AP020320:c173244-173149 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT33299 NZ_AP020320:173064-173121 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References