Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 338774..338954 Replicon chromosome
Accession NZ_CP026953
Organism Staphylococcus aureus strain FDAARGOS_48

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag RL06_RS14940 Protein ID WP_001801861.1
Coordinates 338774..338869 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 338897..338954 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RL06_RS01690 333937..334587 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
RL06_RS01695 334668..335663 + 996 WP_000070642.1 DUF4352 domain-containing protein -
RL06_RS01700 335738..336364 + 627 WP_016170738.1 hypothetical protein -
RL06_RS01705 336405..336746 + 342 WP_000627540.1 DUF3969 family protein -
RL06_RS01710 336847..337419 + 573 WP_000414216.1 hypothetical protein -
RL06_RS01715 337617..338629 - 1013 Protein_331 IS3 family transposase -
RL06_RS14940 338774..338869 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 338897..338954 - 58 - - Antitoxin
RL06_RS01720 338992..339093 + 102 WP_001792025.1 hypothetical protein -
RL06_RS01725 339071..339232 - 162 Protein_334 transposase -
RL06_RS01730 339223..339717 - 495 Protein_335 transposase -
RL06_RS01735 340169..341398 - 1230 WP_000072627.1 restriction endonuclease subunit S -
RL06_RS01740 341391..342947 - 1557 WP_000028669.1 type I restriction-modification system subunit M -
RL06_RS01745 343111..343245 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 333179..365786 32607


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T96773 WP_001801861.1 NZ_CP026953:338774-338869 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T96773 NZ_CP026953:338774-338869 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT96773 NZ_CP026953:c338954-338897 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References