157272

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 173221..173401 Replicon chromosome
Accession NZ_CP053636
Organism Staphylococcus aureus strain 14640

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag HA037_RS01090 Protein ID WP_001801861.1
Coordinates 173306..173401 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 173221..173278 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HA037_RS01060 168930..169064 + 135 WP_001791797.1 hypothetical protein -
HA037_RS01065 169228..170784 + 1557 WP_000028669.1 type I restriction-modification system subunit M -
HA037_RS01070 170777..172006 + 1230 WP_000072627.1 restriction endonuclease subunit S -
HA037_RS01075 172458..172952 + 495 Protein_175 transposase -
HA037_RS01080 172943..173104 + 162 Protein_176 transposase -
HA037_RS01085 173082..173183 - 102 WP_001792025.1 hypothetical protein -
- 173221..173278 + 58 - - Antitoxin
HA037_RS01090 173306..173401 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
HA037_RS01095 173546..174558 + 1013 Protein_179 IS3 family transposase -
HA037_RS01100 174756..175328 - 573 WP_000414216.1 hypothetical protein -
HA037_RS01105 175429..175770 - 342 WP_000627540.1 DUF3969 family protein -
HA037_RS01110 175811..176437 - 627 WP_000669024.1 hypothetical protein -
HA037_RS01115 176512..177507 - 996 WP_000070642.1 DUF4352 domain-containing protein -
HA037_RS01120 177588..178238 - 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - selk / hlgA / lukD 146389..178996 32607


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T157272 WP_001801861.1 NZ_CP053636:c173401-173306 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T157272 NZ_CP069132:c1265797-1265690 [Escherichia coli BW25113]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 58 bp

>AT157272 NZ_CP053636:173221-173278 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References