Detailed information of TA system TA157251

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 173221..173401
• Replicon: chromosome
• Accession: NZ_CP053634
• Organism: Staphylococcus aureus strain 14638

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: HA038_RS01085
• Protein ID: WP_001801861.1
• Coordinates: 173306..173401 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	173221..173278 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HA038_RS01055	168930..169064	+	135	WP_001791797.1	hypothetical protein	-
HA038_RS01060	169228..170784	+	1557	WP_000028669.1	type I restriction-modification system subunit M	-
HA038_RS01065	170777..172006	+	1230	WP_000072627.1	restriction endonuclease subunit S	-
HA038_RS01070	172458..172952	+	495	Protein_174	transposase	-
HA038_RS01075	172943..173104	+	162	Protein_175	transposase	-
HA038_RS01080	173082..173183	-	102	WP_001792025.1	hypothetical protein	-
-	173221..173278	+	58	-	-	Antitoxin
HA038_RS01085	173306..173401	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
HA038_RS01090	173546..174558	+	1013	Protein_178	IS3 family transposase	-
HA038_RS01095	174756..175328	-	573	WP_000414216.1	hypothetical protein	-
HA038_RS01100	175429..175770	-	342	WP_000627540.1	DUF3969 family protein	-
HA038_RS01105	175811..176437	-	627	WP_000669024.1	hypothetical protein	-
HA038_RS01110	176512..177507	-	996	WP_000070642.1	DUF4352 domain-containing protein	-
HA038_RS01115	177588..178238	-	651	WP_001795210.1	excalibur calcium-binding domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	Similar MGE(s) Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE. Detail Genome accession Organism MGE type Related TA Coordinates Mash distance View NC_002745 Staphylococcus aureus subsp. aureus N315 Prophage TA020384 1850940..1883547 0	inside	Prophage	-	selk / hlgA / lukD	146389..178996	32607

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T157251 WP_001801861.1 NZ_CP053634:c173401-173306 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T157251 NZ_CP069080:c3073821-3073246 [Pseudomonas putida]
ATGAGGCATTCCCCCTTCACGGCCGTCTACGACGCATGCGTTCTCTATCCCGCTCCGCTGCGGGACTTCCTGATGTGGCT
GGGGCTGTCCGGTCGGTTCCGAGCGCGTTGGAGCCAAACCATTCACGAGGAGTGGAAACGCAACCTGCTGATCAATCGGC
TCGATCTCACCAGGGCGCAAGTTGACCGAACGTCTGACCTGATGGATCGTGCCATCCCCGATGGATTGGTAGAAGGGTAC
GAATCGCTCGCGGCCGGTCTGACCTTGCCAGATCCGGACGACCGCCACGTGCTGGCCGCCGCCATTCGCTGTGGGGCGAG
TGTGATCGTGACATTCAACCAGCGAGATTTCCCGAATGAGCTGCTGGCGCCCTACGGCGTCGAATCGCAGCATCCGGATG
AGTTCGTGGACAACTTGCTGGATCTGGATGCGGCTGCAGTCGTCTCGGCCGCACAGCGCCAGCGCGCCCAACTGAGGAAC
CCGACGATCGACGTCGATCGCTATCTCGATATCTTGCTGCGCCAAGGCCTGGTCCAGACCACCAAGGTGCTTGCCGGCTA
CCGCACTATCCTCTGA

Antitoxin

Nucleotide

• Length: 58 bp

>AT157251 NZ_CP053634:173221-173278 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin