Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1879139..1879319 Replicon chromosome
Accession NC_013450
Organism Staphylococcus aureus subsp. aureus ED98

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag SAAV_RS15280 Protein ID WP_114579884.1
Coordinates 1879139..1879234 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1879262..1879319 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAAV_RS09295 1874302..1874952 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
SAAV_RS09300 1875033..1876028 + 996 WP_000070642.1 DUF4352 domain-containing protein -
SAAV_RS09305 1876103..1876729 + 627 WP_000669024.1 hypothetical protein -
SAAV_RS09310 1876770..1877111 + 342 WP_000627540.1 DUF3969 family protein -
SAAV_RS09315 1877212..1877784 + 573 WP_000414216.1 hypothetical protein -
SAAV_RS14935 1877982..1878994 - 1013 Protein_1788 IS3 family transposase -
SAAV_RS15280 1879139..1879234 + 96 WP_114579884.1 type I toxin-antitoxin system Fst family toxin Toxin
- 1879262..1879319 - 58 - - Antitoxin
SAAV_RS09335 1879357..1879458 + 102 WP_001792025.1 hypothetical protein -
SAAV_RS15285 1879436..1879597 - 162 Protein_1791 transposase -
SAAV_RS09340 1879588..1880082 - 495 Protein_1792 transposase -
SAAV_RS09345 1880534..1881763 - 1230 WP_000072627.1 restriction endonuclease subunit S -
SAAV_RS09350 1881756..1883312 - 1557 WP_000028669.1 type I restriction-modification system subunit M -
SAAV_RS09355 1883476..1883610 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 1873544..1906152 32608


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3570.36 Da        Isoelectric Point: 10.4449

>T24411 WP_114579884.1 NC_013450:1879139-1879234 [Staphylococcus aureus subsp. aureus ED98]
VMLIFVHIIALVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T24411 NC_013450:1879139-1879234 [Staphylococcus aureus subsp. aureus ED98]
GTGATGCTTATTTTCGTTCACATCATAGCACTAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT24411 NC_013450:c1879319-1879262 [Staphylococcus aureus subsp. aureus ED98]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References