Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 50853..51033 Replicon chromosome
Accession NZ_CP077859
Organism Staphylococcus aureus strain AC5

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag KU537_RS00305 Protein ID WP_001801861.1
Coordinates 50938..51033 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 50853..50910 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KU537_RS00275 46562..46696 + 135 WP_001791797.1 hypothetical protein -
KU537_RS00280 46860..48416 + 1557 WP_000028669.1 type I restriction-modification system subunit M -
KU537_RS00285 48409..49638 + 1230 WP_000072627.1 restriction endonuclease subunit S -
KU537_RS00290 50180..50590 + 411 WP_001808705.1 IS21 family transposase -
KU537_RS00295 50575..50736 + 162 Protein_50 transposase -
KU537_RS00300 50714..50815 - 102 WP_001792025.1 hypothetical protein -
- 50853..50910 + 58 - - Antitoxin
KU537_RS00305 50938..51033 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
KU537_RS00310 51178..52190 + 1013 Protein_53 IS3 family transposase -
KU537_RS00315 52388..52960 - 573 WP_000414216.1 hypothetical protein -
KU537_RS00320 53061..53402 - 342 WP_000627540.1 DUF3969 family protein -
KU537_RS00325 53443..54069 - 627 WP_000669024.1 hypothetical protein -
KU537_RS00330 54145..55140 - 996 WP_000070642.1 DUF4352 domain-containing protein -
KU537_RS00335 55221..55871 - 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - selk / hlgA / lukD 24020..56629 32609


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T208202 WP_001801861.1 NZ_CP077859:c51033-50938 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T208202 NZ_CP103592:643205-643519 [Escherichia coli O25b:H4-ST131]
ATGCACCTGATAACTCAAAAAGCATTGAAAGATGCTGCGGAAAAATACCCGCAACATAAAACGGAGTTGGTGGCTCTGGG
GAACACGATTGCTAAGGGATATTTCAAAAAACCTGAGTCATTAAAAGCAGTATTCCCTTCTCTGGATAACTTCAAATATC
TGGATAAGCATTATGTTTTCAATGTCGGGGGCAATGAATTACGTGTTGTAGCAATGGTCTTTTTTGAATCGCAAAAGTGC
TACATACGTGAAGTTATGACGCATAAAGAATACGATTTCTTTACCGCCGTTCATCGTACTAAGGGGAAAAAATGA

Antitoxin


Download         Length: 58 bp

>AT208202 NZ_CP077859:50853-50910 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References