Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1898440..1898620 Replicon chromosome
Accession NZ_CP031779
Organism Staphylococcus aureus strain CFBR-105

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag D1F65_RS09490 Protein ID WP_001801861.1
Coordinates 1898440..1898535 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1898563..1898620 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D1F65_RS09460 1893603..1894253 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
D1F65_RS09465 1894334..1895329 + 996 WP_000070642.1 DUF4352 domain-containing protein -
D1F65_RS09470 1895404..1896030 + 627 WP_000669024.1 hypothetical protein -
D1F65_RS09475 1896071..1896412 + 342 WP_000627540.1 DUF3969 family protein -
D1F65_RS09480 1896513..1897085 + 573 WP_000414216.1 hypothetical protein -
D1F65_RS09485 1897283..1898295 - 1013 Protein_1779 IS3 family transposase -
D1F65_RS09490 1898440..1898535 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1898563..1898620 - 58 - - Antitoxin
D1F65_RS09495 1898658..1898759 + 102 WP_001792025.1 hypothetical protein -
D1F65_RS09500 1898737..1898898 - 162 Protein_1782 transposase -
D1F65_RS09505 1898889..1899383 - 495 Protein_1783 transposase -
D1F65_RS09510 1899835..1901064 - 1230 WP_000072627.1 restriction endonuclease subunit S -
D1F65_RS09515 1901057..1902613 - 1557 WP_000028669.1 type I restriction-modification system subunit M -
D1F65_RS09520 1902777..1902911 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 1892844..1925453 32609


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T110030 WP_001801861.1 NZ_CP031779:1898440-1898535 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T110030 NZ_CP031779:1898440-1898535 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT110030 NZ_CP031779:c1898620-1898563 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References