209199

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1833370..1833550 Replicon chromosome
Accession NZ_CP078521
Organism Staphylococcus aureus strain ATCC 29213

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag KWH15_RS08795 Protein ID WP_001801861.1
Coordinates 1833370..1833465 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1833493..1833550 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KWH15_RS08765 1828533..1829183 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
KWH15_RS08770 1829264..1830259 + 996 WP_000070642.1 DUF4352 domain-containing protein -
KWH15_RS08775 1830334..1830960 + 627 WP_000669024.1 hypothetical protein -
KWH15_RS08780 1831001..1831342 + 342 WP_000627540.1 DUF3969 family protein -
KWH15_RS08785 1831443..1832015 + 573 WP_000414216.1 hypothetical protein -
KWH15_RS08790 1832213..1833225 - 1013 Protein_1729 IS3 family transposase -
KWH15_RS08795 1833370..1833465 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1833493..1833550 - 58 - - Antitoxin
KWH15_RS08800 1833588..1833689 + 102 WP_001792025.1 hypothetical protein -
KWH15_RS08805 1833667..1833828 - 162 Protein_1732 transposase -
KWH15_RS08810 1833813..1834223 - 411 WP_001808705.1 IS21 family transposase -
KWH15_RS08815 1834765..1835994 - 1230 WP_000072627.1 restriction endonuclease subunit S -
KWH15_RS08820 1835987..1837543 - 1557 WP_071621388.1 type I restriction-modification system subunit M -
KWH15_RS08825 1837707..1837841 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 1827775..1860381 32606


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T209199 WP_001801861.1 NZ_CP078521:1833370-1833465 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T209199 NZ_CP103902:c995426-995163 [Corynebacterium diphtheriae bv. mitis]
GTGGCTTGGGAGATTAGTTTTTCTCCTCGGGCGGTGAAGTCGTTTAAGAAGCTCGATACGGGTGAGCAGCGGAGGGTGAG
TAAGTTTCTGCGGGAGGTTGGCGCCCTTGAGGACCCGAGGTTACGAGGTAAGGCATTAACAGCCAATAAGTCGGGTTTGT
GGCGCTGGCGTGTGGGGGACTATCGGATTATTGCTGACATTGTGGACGCGCGTGTTGTCGTCGTTGTGGTTGACGTTGGG
CACCGCTCGAAGGTCTACGACTAA

Antitoxin


Download         Length: 58 bp

>AT209199 NZ_CP078521:c1833550-1833493 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References