231986

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1742319..1742499 Replicon chromosome
Accession NZ_CP090873
Organism Staphylococcus aureus strain SAUR_BFS16

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag L1A02_RS08840 Protein ID WP_001801861.1
Coordinates 1742404..1742499 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1742319..1742376 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L1A02_RS08810 1738028..1738162 + 135 WP_001791797.1 hypothetical protein -
L1A02_RS08815 1738326..1739882 + 1557 WP_000028669.1 type I restriction-modification system subunit M -
L1A02_RS08820 1739875..1741104 + 1230 WP_000072627.1 restriction endonuclease subunit S -
L1A02_RS08825 1741646..1742056 + 411 WP_001808705.1 IS21 family transposase -
L1A02_RS08830 1742041..1742202 + 162 Protein_1692 transposase -
L1A02_RS08835 1742180..1742281 - 102 WP_001792025.1 hypothetical protein -
- 1742319..1742376 + 58 - - Antitoxin
L1A02_RS08840 1742404..1742499 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
L1A02_RS08845 1742644..1743656 + 1013 Protein_1695 IS3 family transposase -
L1A02_RS08850 1743854..1744426 - 573 WP_000414216.1 hypothetical protein -
L1A02_RS08855 1744527..1744868 - 342 WP_000627540.1 DUF3969 family protein -
L1A02_RS08860 1744909..1745535 - 627 WP_000669024.1 hypothetical protein -
L1A02_RS08865 1745610..1746605 - 996 WP_000070642.1 DUF4352 domain-containing protein -
L1A02_RS08870 1746686..1747336 - 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - selk / hlgA / lukD 1715486..1748094 32608


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T231986 WP_001801861.1 NZ_CP090873:c1742499-1742404 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T231986 NZ_CP127101:990110-990271 [Staphylococcus pseudintermedius]
ATGAAAGACGAACAAAAGCATTATGATAATGAAATGGTTGATAGTTTTGATGATGTTGTGGAGCTCGGTAAAGAAATGGA
ACAAATTTCTGAAGCGAACGATGAAGAGAAACTCAATCAAGCACATGATTCCAAAGTGCGTTCTGATAAAAATACAAAAT
AA

Antitoxin


Download         Length: 58 bp

>AT231986 NZ_CP090873:1742319-1742376 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References