38067

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1895242..1895422 Replicon chromosome
Accession NZ_AP024170
Organism Staphylococcus aureus strain 834

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag SA834_RS09095 Protein ID WP_001801861.1
Coordinates 1895242..1895337 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1895365..1895422 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SA834_RS09065 1890405..1891055 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
SA834_RS09070 1891136..1892131 + 996 WP_000070642.1 DUF4352 domain-containing protein -
SA834_RS09075 1892206..1892832 + 627 WP_000669024.1 hypothetical protein -
SA834_RS09080 1892873..1893214 + 342 WP_000627540.1 DUF3969 family protein -
SA834_RS09085 1893315..1893887 + 573 WP_000414216.1 hypothetical protein -
SA834_RS09090 1894085..1895097 - 1013 Protein_1791 IS3 family transposase -
SA834_RS09095 1895242..1895337 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1895365..1895422 - 58 - - Antitoxin
SA834_RS09100 1895460..1895561 + 102 WP_001792025.1 hypothetical protein -
SA834_RS09105 1895539..1895700 - 162 Protein_1794 transposase -
SA834_RS09110 1895691..1896185 - 495 Protein_1795 transposase -
SA834_RS09115 1896637..1897866 - 1230 WP_000072627.1 restriction endonuclease subunit S -
SA834_RS09120 1897859..1899415 - 1557 WP_000028669.1 type I restriction-modification system subunit M -
SA834_RS09125 1899579..1899713 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 1890441..1931220 40779


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T38067 WP_001801861.1 NZ_AP024170:1895242-1895337 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T38067 NZ_AP024170:1895242-1895337 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT38067 NZ_AP024170:c1895422-1895365 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References