Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 173124..173304 Replicon chromosome
Accession NZ_CP062356
Organism Staphylococcus aureus strain NAS_AN_203

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag IF727_RS01080 Protein ID WP_001801861.1
Coordinates 173209..173304 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 173124..173181 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IF727_RS01050 168833..168967 + 135 WP_001791797.1 hypothetical protein -
IF727_RS01055 169131..170687 + 1557 WP_000028669.1 type I restriction-modification system subunit M -
IF727_RS01060 170680..171909 + 1230 WP_000072627.1 restriction endonuclease subunit S -
IF727_RS01065 172451..172861 + 411 WP_001808705.1 IS21 family transposase -
IF727_RS01070 172846..173007 + 162 Protein_175 transposase -
IF727_RS01075 172985..173086 - 102 WP_001792025.1 hypothetical protein -
- 173124..173181 + 58 - - Antitoxin
IF727_RS01080 173209..173304 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
IF727_RS01085 173449..174461 + 1013 Protein_178 IS3 family transposase -
IF727_RS01090 174659..175231 - 573 WP_000414216.1 hypothetical protein -
IF727_RS01095 175332..175673 - 342 WP_000627540.1 DUF3969 family protein -
IF727_RS01100 175714..176340 - 627 WP_000669024.1 hypothetical protein -
IF727_RS01105 176415..177410 - 996 WP_000070642.1 DUF4352 domain-containing protein -
IF727_RS01110 177491..178141 - 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - selk / hlgA / lukD 146291..178899 32608


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T174553 WP_001801861.1 NZ_CP062356:c173304-173209 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T174553 NZ_CP081189:c4737733-4737422 [Salmonella enterica]
ATGCAATTTATAGAAACGGAACTCTTTACTGAAGATGTTAAAAAACTGCTCGATGATGATGAATACCATAAGCTTCAGGT
TTTTATGGCTCAGCATCCAGATTGTGGTGATGTCATTCAGGAAACGGGCGGCCTGAGAAAAATGCGCTGGGGAGCGCGAG
GCAAAGGAAAGCGTAGTGGCGTGCGAATTATCTATTTTCACCGTAGTCAACGGTATGAGATTCGCTTGCTTCTGATTTAT
CAAAAAGGCATTAAAGATGATCTCACGCCGCAGGAAAAAGCGGTGCTTCGTATGCTGAATGAGAGGTGGTAG

Antitoxin


Download         Length: 58 bp

>AT174553 NZ_CP062356:173124-173181 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References