Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1184591..1184771 Replicon chromosome
Accession NZ_CP022894
Organism Staphylococcus aureus strain 191

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag CGP90_RS06375 Protein ID WP_001801861.1
Coordinates 1184676..1184771 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1184591..1184648 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CGP90_RS06345 1180300..1180434 + 135 WP_001791797.1 hypothetical protein -
CGP90_RS06350 1180598..1182154 + 1557 WP_000028669.1 type I restriction-modification system subunit M -
CGP90_RS06355 1182147..1183376 + 1230 WP_000072627.1 restriction endonuclease subunit S -
CGP90_RS06360 1183828..1184322 + 495 Protein_1142 transposase -
CGP90_RS06365 1184313..1184474 + 162 Protein_1143 transposase -
CGP90_RS06370 1184452..1184553 - 102 WP_001792025.1 hypothetical protein -
- 1184591..1184648 + 58 - - Antitoxin
CGP90_RS06375 1184676..1184771 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
CGP90_RS06380 1184916..1185928 + 1013 Protein_1146 IS3 family transposase -
CGP90_RS06385 1186126..1186698 - 573 WP_000414216.1 hypothetical protein -
CGP90_RS06390 1186799..1187140 - 342 WP_000627540.1 DUF3969 family protein -
CGP90_RS06395 1187181..1187807 - 627 WP_000669024.1 hypothetical protein -
CGP90_RS06400 1187882..1188877 - 996 WP_000070642.1 DUF4352 domain-containing protein -
CGP90_RS06405 1188958..1189608 - 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - selk / hlgA / lukD 1155094..1189572 34478


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T79888 WP_001801861.1 NZ_CP022894:c1184771-1184676 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T79888 NZ_CP022894:c1184771-1184676 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT79888 NZ_CP022894:1184591-1184648 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References