92986

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 2703434..2703614 Replicon chromosome
Accession NZ_CP026063
Organism Staphylococcus aureus strain FDAARGOS_14

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag RK72_RS14385 Protein ID WP_001801861.1
Coordinates 2703434..2703529 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2703557..2703614 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RK72_RS13880 2698597..2699247 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
RK72_RS13885 2699328..2700323 + 996 WP_000070642.1 DUF4352 domain-containing protein -
RK72_RS13890 2700398..2701024 + 627 WP_000669024.1 hypothetical protein -
RK72_RS13895 2701065..2701406 + 342 WP_000627540.1 DUF3969 family protein -
RK72_RS13900 2701507..2702079 + 573 WP_000414216.1 hypothetical protein -
RK72_RS13905 2702277..2703289 - 1013 Protein_2599 IS3 family transposase -
RK72_RS14385 2703434..2703529 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 2703557..2703614 - 58 - - Antitoxin
RK72_RS13910 2703652..2703753 + 102 WP_001792025.1 hypothetical protein -
RK72_RS13915 2703731..2703892 - 162 Protein_2602 transposase -
RK72_RS13920 2703883..2704377 - 495 Protein_2603 transposase -
RK72_RS13925 2704829..2706058 - 1230 WP_000072627.1 restriction endonuclease subunit S -
RK72_RS13930 2706051..2707607 - 1557 WP_000028669.1 type I restriction-modification system subunit M -
RK72_RS13935 2707771..2707905 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 2697839..2730447 32608


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T92986 WP_001801861.1 NZ_CP026063:2703434-2703529 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T92986 NZ_CP026063:2703434-2703529 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT92986 NZ_CP026063:c2703614-2703557 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References