Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1803871..1804051 Replicon chromosome
Accession NZ_CP017677
Organism Staphylococcus aureus strain CFSAN007894

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag AB466_RS14210 Protein ID WP_001801861.1
Coordinates 1803871..1803966 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1803994..1804051 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AB466_RS08865 1799034..1799684 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
AB466_RS08870 1799765..1800760 + 996 WP_000070642.1 DUF4352 domain-containing protein -
AB466_RS08875 1800835..1801461 + 627 WP_000669024.1 hypothetical protein -
AB466_RS08880 1801502..1801843 + 342 WP_000627540.1 DUF3969 family protein -
AB466_RS08885 1801944..1802516 + 573 WP_000414216.1 hypothetical protein -
AB466_RS08890 1802714..1803726 - 1013 Protein_1669 IS3 family transposase -
AB466_RS14210 1803871..1803966 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1803994..1804051 - 58 - - Antitoxin
AB466_RS08895 1804089..1804190 + 102 WP_001792025.1 hypothetical protein -
AB466_RS08900 1804168..1804329 - 162 Protein_1672 transposase -
AB466_RS08905 1804320..1804814 - 495 Protein_1673 transposase -
AB466_RS08910 1805266..1806495 - 1230 WP_000072627.1 restriction endonuclease subunit S -
AB466_RS08915 1806488..1808044 - 1557 WP_000028669.1 type I restriction-modification system subunit M -
AB466_RS08920 1808208..1808342 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 1798276..1831760 33484


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T67975 WP_001801861.1 NZ_CP017677:1803871-1803966 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T67975 NZ_CP017677:1803871-1803966 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT67975 NZ_CP017677:c1804051-1803994 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References