Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1857087..1857267 Replicon chromosome
Accession NZ_CP017682
Organism Staphylococcus aureus strain CFSAN007850

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag AB526_RS14660 Protein ID WP_001801861.1
Coordinates 1857087..1857182 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1857210..1857267 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AB526_RS09235 1852250..1852900 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
AB526_RS09240 1852981..1853976 + 996 WP_000070642.1 DUF4352 domain-containing protein -
AB526_RS09245 1854051..1854677 + 627 WP_000669024.1 hypothetical protein -
AB526_RS09250 1854718..1855059 + 342 WP_000627540.1 DUF3969 family protein -
AB526_RS09255 1855160..1855732 + 573 WP_000414216.1 hypothetical protein -
AB526_RS09260 1855930..1856942 - 1013 Protein_1749 IS3 family transposase -
AB526_RS14660 1857087..1857182 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1857210..1857267 - 58 - - Antitoxin
AB526_RS09265 1857305..1857406 + 102 WP_001792025.1 hypothetical protein -
AB526_RS09270 1857384..1857545 - 162 Protein_1752 transposase -
AB526_RS09275 1857536..1858030 - 495 Protein_1753 transposase -
AB526_RS09280 1858482..1859711 - 1230 WP_000072627.1 restriction endonuclease subunit S -
AB526_RS09285 1859704..1861260 - 1557 WP_000028669.1 type I restriction-modification system subunit M -
AB526_RS09290 1861424..1861558 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 1851492..1884088 32596


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T68018 WP_001801861.1 NZ_CP017682:1857087-1857182 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T68018 NZ_CP017682:1857087-1857182 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT68018 NZ_CP017682:c1857267-1857210 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References