Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1891371..1891551 Replicon chromosome
Accession NZ_CP034005
Organism Staphylococcus aureus strain P1D7C1

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag EFD70_RS09105 Protein ID WP_001801861.1
Coordinates 1891371..1891466 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1891494..1891551 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EFD70_RS09075 1886534..1887184 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
EFD70_RS09080 1887265..1888260 + 996 WP_000070642.1 DUF4352 domain-containing protein -
EFD70_RS09085 1888335..1888961 + 627 WP_000669024.1 hypothetical protein -
EFD70_RS09090 1889002..1889343 + 342 WP_000627540.1 DUF3969 family protein -
EFD70_RS09095 1889444..1890016 + 573 WP_000414216.1 hypothetical protein -
EFD70_RS09100 1890214..1891226 - 1013 Protein_1776 IS3 family transposase -
EFD70_RS09105 1891371..1891466 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1891494..1891551 - 58 - - Antitoxin
EFD70_RS09110 1891589..1891690 + 102 WP_001792025.1 hypothetical protein -
EFD70_RS09115 1891668..1891829 - 162 Protein_1779 transposase -
EFD70_RS09120 1891820..1892314 - 495 Protein_1780 transposase -
EFD70_RS09125 1892766..1893995 - 1230 WP_000072627.1 restriction endonuclease subunit S -
EFD70_RS09130 1893988..1895544 - 1557 WP_064135920.1 type I restriction-modification system subunit M -
EFD70_RS09135 1895708..1895842 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 1885776..1920177 34401


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T114890 WP_001801861.1 NZ_CP034005:1891371-1891466 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T114890 NZ_CP034005:1891371-1891466 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT114890 NZ_CP034005:c1891551-1891494 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References