Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1906685..1906865 Replicon chromosome
Accession NZ_CP042153
Organism Staphylococcus aureus strain B4-59C

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag FP482_RS09245 Protein ID WP_001801861.1
Coordinates 1906685..1906780 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1906808..1906865 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FP482_RS09215 1901848..1902498 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
FP482_RS09220 1902579..1903574 + 996 WP_000070642.1 DUF4352 domain-containing protein -
FP482_RS09225 1903649..1904275 + 627 WP_000669024.1 hypothetical protein -
FP482_RS09230 1904316..1904657 + 342 WP_000627540.1 DUF3969 family protein -
FP482_RS09235 1904758..1905330 + 573 WP_000414216.1 hypothetical protein -
FP482_RS09240 1905528..1906540 - 1013 Protein_1782 IS3 family transposase -
FP482_RS09245 1906685..1906780 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1906808..1906865 - 58 - - Antitoxin
FP482_RS09250 1906903..1907004 + 102 WP_001792025.1 hypothetical protein -
FP482_RS09255 1906982..1907143 - 162 Protein_1785 transposase -
FP482_RS09260 1907134..1907628 - 495 Protein_1786 transposase -
FP482_RS09265 1908080..1909309 - 1230 WP_000072627.1 restriction endonuclease subunit S -
FP482_RS09270 1909302..1910858 - 1557 WP_000028669.1 type I restriction-modification system subunit M -
FP482_RS09275 1911022..1911156 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 1901090..1933696 32606


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T134888 WP_001801861.1 NZ_CP042153:1906685-1906780 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T134888 NZ_CP042153:1906685-1906780 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT134888 NZ_CP042153:c1906865-1906808 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References