70414

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1973324..1973504 Replicon chromosome
Accession NZ_CP018766
Organism Staphylococcus aureus strain UCI62

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag BSG38_RS15625 Protein ID WP_001801861.1
Coordinates 1973324..1973419 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1973447..1973504 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSG38_RS10015 1968487..1969137 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
BSG38_RS10020 1969218..1970213 + 996 WP_000070642.1 DUF4352 domain-containing protein -
BSG38_RS10025 1970288..1970914 + 627 WP_000669024.1 hypothetical protein -
BSG38_RS10030 1970955..1971296 + 342 WP_000627540.1 DUF3969 family protein -
BSG38_RS10035 1971397..1971969 + 573 WP_000414216.1 hypothetical protein -
BSG38_RS15475 1972167..1973179 - 1013 Protein_1882 IS3 family transposase -
BSG38_RS15625 1973324..1973419 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1973447..1973504 - 58 - - Antitoxin
BSG38_RS10050 1973542..1973643 + 102 WP_001792025.1 hypothetical protein -
BSG38_RS15630 1973621..1973782 - 162 Protein_1885 transposase -
BSG38_RS10060 1973773..1974267 - 495 Protein_1886 transposase -
BSG38_RS10065 1974719..1975948 - 1230 WP_000072627.1 restriction endonuclease subunit S -
BSG38_RS10070 1975941..1977497 - 1557 WP_000028669.1 type I restriction-modification system subunit M -
BSG38_RS10075 1977661..1977795 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 1967728..2000336 32608


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T70414 WP_001801861.1 NZ_CP018766:1973324-1973419 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T70414 NZ_CP018766:1973324-1973419 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT70414 NZ_CP018766:c1973504-1973447 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References