197309

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 172264..172444 Replicon chromosome
Accession NZ_CP072116
Organism Staphylococcus aureus strain TCH32929

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag J6L63_RS01085 Protein ID WP_001801861.1
Coordinates 172349..172444 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 172264..172321 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J6L63_RS01055 167974..168108 + 135 WP_001791797.1 hypothetical protein -
J6L63_RS01060 168272..169828 + 1557 WP_000028669.1 type I restriction-modification system subunit M -
J6L63_RS01065 169821..171050 + 1230 WP_000072627.1 restriction endonuclease subunit S -
J6L63_RS01070 171591..172001 + 411 WP_001808705.1 IS21 family transposase -
J6L63_RS01075 171986..172147 + 162 Protein_175 transposase -
J6L63_RS01080 172125..172226 - 102 WP_001792025.1 hypothetical protein -
- 172264..172321 + 58 - - Antitoxin
J6L63_RS01085 172349..172444 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
J6L63_RS01090 172589..173601 + 1013 Protein_178 IS3 family transposase -
J6L63_RS01095 173799..174371 - 573 WP_000414216.1 hypothetical protein -
J6L63_RS01100 174472..174813 - 342 WP_000627540.1 DUF3969 family protein -
J6L63_RS01105 174854..175480 - 627 WP_000669024.1 hypothetical protein -
J6L63_RS01110 175555..176550 - 996 WP_000070642.1 DUF4352 domain-containing protein -
J6L63_RS01115 176631..177281 - 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - selk / hlgA / lukD 146309..178039 31730


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T197309 WP_001801861.1 NZ_CP072116:c172444-172349 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T197309 NZ_CP095923:c5289125-5288826 [Pseudomonas aeruginosa]
ATGGTTGAAGTCAAACAAACCGCCACTTTCATGGCATGGGAAAGCAAGCTAAAGGATCGGCGGGCAAAGGCCGTGATCGC
CGCCCGTATCTTCCGATTGGCGAATGGACTACCCGGCGATGTGTCACCAGTCGGCCAGGGTGTGAGCGAGTTGAGGATTC
ACTATGGCCCAGGCTATCGGGTGTACTTCCAGCAGCGCGGGACGGAAATCGTCATCCTGCTATGTGGTGGAGACAAGAGC
AGCCAGGCCAGGGATATAGAAATGGCGAAACGCCTGGCAAATGAGTGGAGGCCGCAATGA

Antitoxin


Download         Length: 58 bp

>AT197309 NZ_CP072116:172264-172321 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References