231957

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 300233..300413 Replicon chromosome
Accession NZ_CP090870
Organism Staphylococcus aureus strain SAUR_BFS62

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag L0999_RS01470 Protein ID WP_001801861.1
Coordinates 300233..300328 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 300356..300413 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0999_RS01440 295396..296046 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
L0999_RS01445 296127..297122 + 996 WP_000070642.1 DUF4352 domain-containing protein -
L0999_RS01450 297197..297823 + 627 WP_000669024.1 hypothetical protein -
L0999_RS01455 297864..298205 + 342 WP_000627540.1 DUF3969 family protein -
L0999_RS01460 298306..298878 + 573 WP_000414216.1 hypothetical protein -
L0999_RS01465 299076..300088 - 1013 Protein_291 IS3 family transposase -
L0999_RS01470 300233..300328 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 300356..300413 - 58 - - Antitoxin
L0999_RS01475 300451..300552 + 102 WP_001792025.1 hypothetical protein -
L0999_RS01480 300530..300691 - 162 Protein_294 transposase -
L0999_RS01485 300676..301086 - 411 WP_001808705.1 IS21 family transposase -
L0999_RS01490 301628..302857 - 1230 WP_000072627.1 restriction endonuclease subunit S -
L0999_RS01495 302850..304406 - 1557 WP_000028669.1 type I restriction-modification system subunit M -
L0999_RS01500 304570..304704 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 294638..329916 35278


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T231957 WP_001801861.1 NZ_CP090870:300233-300328 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T231957 NZ_CP127024:c2059684-2059532 [Staphylococcus aureus]
ATGTCTAAAGACAAAGATCCAAAATTAAATTATCATGAAGAAGAAAACAGTATGGTAACGGATTTTGAAGATTTAAAAGA
ATTAGGTAAAGAAATGGAACAAATCTCTGATCAAAATGATCAAGAAAAGAATTCTGAAGAAGACAGTCAGTAA

Antitoxin


Download         Length: 58 bp

>AT231957 NZ_CP090870:c300413-300356 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References