Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1935727..1935907 Replicon chromosome
Accession NC_009782
Organism Staphylococcus aureus subsp. aureus Mu3

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag SAHV_RS15495 Protein ID WP_001801861.1
Coordinates 1935727..1935822 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1935850..1935907 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAHV_RS09515 1930890..1931540 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
SAHV_RS09520 1931621..1932616 + 996 WP_000070642.1 DUF4352 domain-containing protein -
SAHV_RS09525 1932691..1933317 + 627 WP_000669024.1 hypothetical protein -
SAHV_RS09530 1933358..1933699 + 342 WP_000627540.1 DUF3969 family protein -
SAHV_RS09535 1933800..1934372 + 573 WP_000414216.1 hypothetical protein -
SAHV_RS15115 1934570..1935582 - 1013 Protein_1840 IS3 family transposase -
SAHV_RS15495 1935727..1935822 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1935850..1935907 - 58 - - Antitoxin
SAHV_RS09555 1935945..1936046 + 102 WP_001792025.1 hypothetical protein -
SAHV_RS15500 1936024..1936185 - 162 Protein_1843 transposase -
SAHV_RS09560 1936176..1936670 - 495 Protein_1844 transposase -
SAHV_RS09565 1937122..1938351 - 1230 WP_000072626.1 restriction endonuclease subunit S -
SAHV_RS09570 1938344..1939900 - 1557 WP_000028669.1 type I restriction-modification system subunit M -
SAHV_RS09575 1940064..1940198 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 1930926..1971705 40779


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T22376 WP_001801861.1 NC_009782:1935727-1935822 [Staphylococcus aureus subsp. aureus Mu3]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T22376 NC_009782:1935727-1935822 [Staphylococcus aureus subsp. aureus Mu3]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT22376 NC_009782:c1935907-1935850 [Staphylococcus aureus subsp. aureus Mu3]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References