114782

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1937917..1938097 Replicon chromosome
Accession NZ_CP033982
Organism Staphylococcus aureus strain P2D8C1

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag EFD77_RS09525 Protein ID WP_001801861.1
Coordinates 1937917..1938012 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1938040..1938097 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EFD77_RS09495 1933080..1933730 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
EFD77_RS09500 1933811..1934806 + 996 WP_000070642.1 DUF4352 domain-containing protein -
EFD77_RS09505 1934881..1935507 + 627 WP_000669024.1 hypothetical protein -
EFD77_RS09510 1935548..1935889 + 342 WP_000627540.1 DUF3969 family protein -
EFD77_RS09515 1935990..1936562 + 573 WP_000414216.1 hypothetical protein -
EFD77_RS09520 1936760..1937772 - 1013 Protein_1829 IS3 family transposase -
EFD77_RS09525 1937917..1938012 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1938040..1938097 - 58 - - Antitoxin
EFD77_RS09530 1938135..1938236 + 102 WP_001792025.1 hypothetical protein -
EFD77_RS09535 1938214..1938375 - 162 Protein_1832 transposase -
EFD77_RS09540 1938366..1938860 - 495 Protein_1833 transposase -
EFD77_RS09545 1939312..1940541 - 1230 WP_000072627.1 restriction endonuclease subunit S -
EFD77_RS09550 1940534..1942090 - 1557 WP_064135920.1 type I restriction-modification system subunit M -
EFD77_RS09555 1942254..1942388 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 1932322..1964054 31732


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T114782 WP_001801861.1 NZ_CP033982:1937917-1938012 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T114782 NZ_CP033982:1937917-1938012 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT114782 NZ_CP033982:c1938097-1938040 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References