Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 2313772..2313952 Replicon chromosome
Accession NZ_CP029671
Organism Staphylococcus aureus strain AR_0222

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag CSB78_RS12030 Protein ID WP_001801861.1
Coordinates 2313857..2313952 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2313772..2313829 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSB78_RS12000 2309481..2309615 + 135 WP_001791797.1 hypothetical protein -
CSB78_RS12005 2309779..2311335 + 1557 WP_000028669.1 type I restriction-modification system subunit M -
CSB78_RS12010 2311328..2312557 + 1230 WP_000072627.1 restriction endonuclease subunit S -
CSB78_RS12015 2313009..2313503 + 495 Protein_2170 transposase -
CSB78_RS12020 2313494..2313655 + 162 Protein_2171 transposase -
CSB78_RS12025 2313633..2313734 - 102 WP_001792025.1 hypothetical protein -
- 2313772..2313829 + 58 - - Antitoxin
CSB78_RS12030 2313857..2313952 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
CSB78_RS12035 2314097..2315109 + 1013 Protein_2174 IS3 family transposase -
CSB78_RS12040 2315307..2315879 - 573 WP_000414216.1 hypothetical protein -
CSB78_RS12045 2315980..2316321 - 342 WP_000627540.1 DUF3969 family protein -
CSB78_RS12050 2316362..2316987 - 626 Protein_2177 hypothetical protein -
CSB78_RS12055 2317062..2318057 - 996 WP_000070642.1 DUF4352 domain-containing protein -
CSB78_RS12060 2318138..2318788 - 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - selk / hlgA / lukD 2286939..2318752 31813


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T106252 WP_001801861.1 NZ_CP029671:c2313952-2313857 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T106252 NZ_CP029671:c2313952-2313857 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT106252 NZ_CP029671:2313772-2313829 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References