Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 173254..173434 Replicon chromosome
Accession NZ_CP091525
Organism Staphylococcus aureus strain N09CSA16

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag L4X60_RS01075 Protein ID WP_001801861.1
Coordinates 173339..173434 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 173254..173311 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L4X60_RS01045 168963..169097 + 135 WP_001791797.1 hypothetical protein -
L4X60_RS01050 169261..170817 + 1557 WP_000028663.1 type I restriction-modification system subunit M -
L4X60_RS01055 170810..172039 + 1230 WP_000072627.1 restriction endonuclease subunit S -
L4X60_RS01060 172581..172991 + 411 WP_001808705.1 IS21 family transposase -
L4X60_RS01065 172976..173137 + 162 Protein_173 transposase -
L4X60_RS01070 173115..173216 - 102 WP_001792025.1 hypothetical protein -
- 173254..173311 + 58 - - Antitoxin
L4X60_RS01075 173339..173434 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
L4X60_RS01080 173579..174591 + 1013 Protein_176 IS3 family transposase -
L4X60_RS01085 174789..175361 - 573 WP_000414216.1 hypothetical protein -
L4X60_RS01090 175462..175803 - 342 WP_000627540.1 DUF3969 family protein -
L4X60_RS01095 175844..176470 - 627 WP_000669024.1 hypothetical protein -
L4X60_RS01100 176545..177542 - 998 Protein_180 DUF4352 domain-containing protein -
L4X60_RS01105 177623..178273 - 651 WP_001838777.1 excalibur calcium-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - selk / hlgA / lukD 146422..179031 32609


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T233504 WP_001801861.1 NZ_CP091525:c173434-173339 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T233504 NZ_HG969191:382678-382992 [Bartonella henselae]
ATGATACATAAAAGAACGAATGAAGGTGACTTGGTAATTGAATCTTTTGCGGATAAGCGGTGTAAAGATCTTTTAGAAGG
CAATCCACCTAAAGGTTTTCCCACAACTCTCGTGCGTATAGTCCAACGAAAATTATTTATGCTGGATAAAGCAGTTGATC
TCAAAGATTTACGCAGTCCTCCGGGTAATCGTTTAGATGCATTGAAAGGAGAGCGTAAAGGTCAATATTCTATTCGTATT
AATGACCAGTTTCGCATTTGTTTTGAGTGGCGTTCTAATGGTGCCTATGAAGTTGAAATCATCGATTATCATTGA

Antitoxin


Download         Length: 58 bp

>AT233504 NZ_CP091525:173254-173311 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References