106171

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1009793..1009973 Replicon chromosome
Accession NZ_CP029663
Organism Staphylococcus aureus strain AR_0228

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag CSB84_RS05650 Protein ID WP_001801861.1
Coordinates 1009878..1009973 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1009793..1009850 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSB84_RS05620 1005502..1005636 + 135 WP_001791797.1 hypothetical protein -
CSB84_RS05625 1005800..1007356 + 1557 WP_000028669.1 type I restriction-modification system subunit M -
CSB84_RS05630 1007349..1008578 + 1230 WP_000072627.1 restriction endonuclease subunit S -
CSB84_RS05635 1009030..1009524 + 495 Protein_955 transposase -
CSB84_RS05640 1009515..1009676 + 162 Protein_956 transposase -
CSB84_RS05645 1009654..1009755 - 102 WP_001792025.1 hypothetical protein -
- 1009793..1009850 + 58 - - Antitoxin
CSB84_RS05650 1009878..1009973 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
CSB84_RS05655 1010118..1011130 + 1013 Protein_959 IS3 family transposase -
CSB84_RS05660 1011328..1011900 - 573 WP_000414216.1 hypothetical protein -
CSB84_RS05665 1012001..1012342 - 342 WP_000627540.1 DUF3969 family protein -
CSB84_RS05670 1012383..1013009 - 627 WP_000669024.1 hypothetical protein -
CSB84_RS05675 1013084..1014079 - 996 WP_000070642.1 DUF4352 domain-containing protein -
CSB84_RS05680 1014160..1014810 - 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - selk / hlgA / lukD 982960..1015569 32609


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T106171 WP_001801861.1 NZ_CP029663:c1009973-1009878 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T106171 NZ_CP029663:c1009973-1009878 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT106171 NZ_CP029663:1009793-1009850 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References