Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1667782..1667962 Replicon chromosome
Accession NZ_CP022904
Organism Staphylococcus aureus strain 629

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag CGQ02_RS08535 Protein ID WP_001801861.1
Coordinates 1667782..1667877 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1667905..1667962 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CGQ02_RS08505 1662945..1663595 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
CGQ02_RS08510 1663676..1664671 + 996 WP_000070642.1 DUF4352 domain-containing protein -
CGQ02_RS08515 1664746..1665372 + 627 WP_000669024.1 hypothetical protein -
CGQ02_RS08520 1665413..1665754 + 342 WP_000627540.1 DUF3969 family protein -
CGQ02_RS08525 1665855..1666427 + 573 WP_000414216.1 hypothetical protein -
CGQ02_RS08530 1666625..1667637 - 1013 Protein_1600 IS3 family transposase -
CGQ02_RS08535 1667782..1667877 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1667905..1667962 - 58 - - Antitoxin
CGQ02_RS08540 1668000..1668101 + 102 WP_001792025.1 hypothetical protein -
CGQ02_RS08545 1668079..1668240 - 162 Protein_1603 transposase -
CGQ02_RS08550 1668231..1668725 - 495 Protein_1604 transposase -
CGQ02_RS08555 1669177..1670406 - 1230 WP_000072627.1 restriction endonuclease subunit S -
CGQ02_RS08560 1670399..1671955 - 1557 WP_000028669.1 type I restriction-modification system subunit M -
CGQ02_RS08565 1672119..1672253 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 1662187..1700129 37942


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T80049 WP_001801861.1 NZ_CP022904:1667782-1667877 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T80049 NZ_CP022904:1667782-1667877 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT80049 NZ_CP022904:c1667962-1667905 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References