53562

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1836533..1836713 Replicon chromosome
Accession NZ_CP011147
Organism Staphylococcus aureus strain FCFHV36

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag FCFHV36_RS16275 Protein ID WP_001801861.1
Coordinates 1836533..1836628 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1836656..1836713 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FCFHV36_RS08835 1831696..1832346 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
FCFHV36_RS08840 1832427..1833422 + 996 WP_000070642.1 DUF4352 domain-containing protein -
FCFHV36_RS08845 1833497..1834123 + 627 WP_000669024.1 hypothetical protein -
FCFHV36_RS08850 1834164..1834505 + 342 WP_000627540.1 DUF3969 family protein -
FCFHV36_RS08855 1834606..1835178 + 573 WP_000414216.1 hypothetical protein -
FCFHV36_RS15415 1835376..1836388 - 1013 Protein_1705 IS3 family transposase -
FCFHV36_RS16275 1836533..1836628 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1836656..1836713 - 58 - - Antitoxin
FCFHV36_RS15420 1836751..1836852 + 102 WP_001792025.1 hypothetical protein -
FCFHV36_RS16280 1836830..1836991 - 162 Protein_1708 transposase -
FCFHV36_RS08880 1836982..1837476 - 495 Protein_1709 transposase -
FCFHV36_RS08885 1837928..1839157 - 1230 WP_000072627.1 restriction endonuclease subunit S -
FCFHV36_RS08890 1839150..1840706 - 1557 WP_000028669.1 type I restriction-modification system subunit M -
FCFHV36_RS15425 1840870..1841004 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 1830937..1871635 40698


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T53562 WP_001801861.1 NZ_CP011147:1836533-1836628 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T53562 NZ_CP011147:1836533-1836628 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT53562 NZ_CP011147:c1836713-1836656 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References