Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 2002831..2003011 Replicon chromosome
Accession NZ_CP012692
Organism Staphylococcus aureus strain FORC_027

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag FORC27_RS15820 Protein ID WP_001801861.1
Coordinates 2002831..2002926 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2002954..2003011 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FORC27_RS10030 1997994..1998644 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
FORC27_RS10035 1998725..1999720 + 996 WP_000070642.1 DUF4352 domain-containing protein -
FORC27_RS10040 1999795..2000421 + 627 WP_000669024.1 hypothetical protein -
FORC27_RS10045 2000462..2000803 + 342 WP_000627540.1 DUF3969 family protein -
FORC27_RS10050 2000904..2001476 + 573 WP_000414216.1 hypothetical protein -
FORC27_RS15645 2001674..2002686 - 1013 Protein_1942 IS3 family transposase -
FORC27_RS15820 2002831..2002926 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 2002954..2003011 - 58 - - Antitoxin
FORC27_RS10070 2003049..2003150 + 102 WP_001792025.1 hypothetical protein -
FORC27_RS15825 2003128..2003289 - 162 Protein_1945 transposase -
FORC27_RS10075 2003280..2003774 - 495 Protein_1946 transposase -
FORC27_RS10080 2004226..2005455 - 1230 WP_000072626.1 restriction endonuclease subunit S -
FORC27_RS10085 2005448..2007004 - 1557 WP_000028669.1 type I restriction-modification system subunit M -
FORC27_RS10090 2007168..2007302 - 135 WP_069479482.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 1997236..2029843 32607


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T56989 WP_001801861.1 NZ_CP012692:2002831-2002926 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T56989 NZ_CP012692:2002831-2002926 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT56989 NZ_CP012692:c2003011-2002954 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References