Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 174451..174631 Replicon chromosome
Accession NZ_CP047865
Organism Staphylococcus aureus strain UP_844

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag E3S61_RS01085 Protein ID WP_001801861.1
Coordinates 174536..174631 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 174451..174508 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3S61_RS01055 170160..170294 + 135 WP_001791797.1 hypothetical protein -
E3S61_RS01060 170458..172014 + 1557 WP_000028669.1 type I restriction-modification system subunit M -
E3S61_RS01065 172007..173236 + 1230 WP_000072627.1 restriction endonuclease subunit S -
E3S61_RS01070 173688..174182 + 495 Protein_175 transposase -
E3S61_RS01075 174173..174334 + 162 Protein_176 transposase -
E3S61_RS01080 174312..174413 - 102 WP_001792025.1 hypothetical protein -
- 174451..174508 + 58 - - Antitoxin
E3S61_RS01085 174536..174631 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
E3S61_RS01090 174776..175788 + 1013 Protein_179 IS3 family transposase -
E3S61_RS01095 175986..176558 - 573 WP_000414216.1 hypothetical protein -
E3S61_RS01100 176659..177000 - 342 WP_000627540.1 DUF3969 family protein -
E3S61_RS01105 177041..177667 - 627 WP_000669024.1 hypothetical protein -
E3S61_RS01110 177742..178737 - 996 WP_000070642.1 DUF4352 domain-containing protein -
E3S61_RS01115 178818..179468 - 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - selk / hlgA / lukD 147620..179432 31812


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T148424 WP_001801861.1 NZ_CP047865:c174631-174536 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T148424 NZ_CP063515:c4304592-4304374 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGTCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCTGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 58 bp

>AT148424 NZ_CP047865:174451-174508 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References