Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1528866..1529046 Replicon chromosome
Accession NZ_CP029655
Organism Staphylococcus aureus strain AR_0469

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag CSC54_RS08255 Protein ID WP_001801861.1
Coordinates 1528951..1529046 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1528866..1528923 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSC54_RS08225 1524575..1524709 + 135 WP_001791797.1 hypothetical protein -
CSC54_RS08230 1524873..1526429 + 1557 WP_000028669.1 type I restriction-modification system subunit M -
CSC54_RS08235 1526422..1527651 + 1230 WP_000072627.1 restriction endonuclease subunit S -
CSC54_RS08240 1528103..1528597 + 495 Protein_1460 transposase -
CSC54_RS08245 1528588..1528749 + 162 Protein_1461 transposase -
CSC54_RS08250 1528727..1528828 - 102 WP_001792025.1 hypothetical protein -
- 1528866..1528923 + 58 - - Antitoxin
CSC54_RS08255 1528951..1529046 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
CSC54_RS08260 1529191..1530203 + 1013 Protein_1464 IS3 family transposase -
CSC54_RS08265 1530401..1530973 - 573 WP_000414216.1 hypothetical protein -
CSC54_RS08270 1531074..1531415 - 342 WP_000627540.1 DUF3969 family protein -
CSC54_RS08275 1531456..1532082 - 627 WP_000669024.1 hypothetical protein -
CSC54_RS08280 1532157..1533152 - 996 WP_000070642.1 DUF4352 domain-containing protein -
CSC54_RS08285 1533233..1533883 - 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - selk / hlgA / lukD 1502033..1534642 32609


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T106121 WP_001801861.1 NZ_CP029655:c1529046-1528951 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T106121 NZ_CP029655:c1529046-1528951 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT106121 NZ_CP029655:1528866-1528923 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References