33343

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 174553..174733 Replicon chromosome
Accession NZ_AP020324
Organism Staphylococcus aureus strain KUN1163

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag KUH140013_RS01125 Protein ID WP_001801861.1
Coordinates 174638..174733 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 174553..174610 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KUH140013_RS01095 170262..170396 + 135 WP_001791797.1 hypothetical protein -
KUH140013_RS01100 170560..172116 + 1557 WP_000028669.1 type I restriction-modification system subunit M -
KUH140013_RS01105 172109..173338 + 1230 WP_000072627.1 restriction endonuclease subunit S -
KUH140013_RS01110 173790..174284 + 495 Protein_175 transposase -
KUH140013_RS01115 174275..174436 + 162 Protein_176 transposase -
KUH140013_RS01120 174414..174515 - 102 WP_001792025.1 hypothetical protein -
- 174553..174610 + 58 - - Antitoxin
KUH140013_RS01125 174638..174733 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
KUH140013_RS01130 174878..175890 + 1013 Protein_179 IS3 family transposase -
KUH140013_RS01135 176088..176660 - 573 WP_000414216.1 hypothetical protein -
KUH140013_RS01140 176761..177102 - 342 WP_000627540.1 DUF3969 family protein -
KUH140013_RS01145 177143..177769 - 627 WP_000669024.1 hypothetical protein -
KUH140013_RS01150 177844..178839 - 996 WP_000070642.1 DUF4352 domain-containing protein -
KUH140013_RS01155 178920..179570 - 651 WP_001838777.1 excalibur calcium-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - selk / hlgA / lukD 147721..179534 31813


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T33343 WP_001801861.1 NZ_AP020324:c174733-174638 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T33343 NZ_AP020324:c174733-174638 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT33343 NZ_AP020324:174553-174610 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References