106255

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1900925..1901105 Replicon chromosome
Accession NZ_CP029673
Organism Staphylococcus aureus strain AR_0220

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag CSB76_RS09665 Protein ID WP_001801861.1
Coordinates 1900925..1901020 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1901048..1901105 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSB76_RS09635 1896088..1896738 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
CSB76_RS09640 1896819..1897814 + 996 WP_000070642.1 DUF4352 domain-containing protein -
CSB76_RS09645 1897889..1898515 + 627 WP_000669024.1 hypothetical protein -
CSB76_RS09650 1898556..1898897 + 342 WP_000627540.1 DUF3969 family protein -
CSB76_RS09655 1898998..1899570 + 573 WP_000414216.1 hypothetical protein -
CSB76_RS09660 1899768..1900780 - 1013 Protein_1779 IS3 family transposase -
CSB76_RS09665 1900925..1901020 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1901048..1901105 - 58 - - Antitoxin
CSB76_RS09670 1901143..1901244 + 102 WP_001792025.1 hypothetical protein -
CSB76_RS09675 1901222..1901383 - 162 Protein_1782 transposase -
CSB76_RS09680 1901374..1901868 - 495 Protein_1783 transposase -
CSB76_RS09685 1902320..1903549 - 1230 WP_000072627.1 restriction endonuclease subunit S -
CSB76_RS09690 1903542..1905098 - 1557 WP_000028669.1 type I restriction-modification system subunit M -
CSB76_RS09695 1905262..1905396 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 1895330..1930607 35277


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T106255 WP_001801861.1 NZ_CP029673:1900925-1901020 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T106255 NZ_CP029673:1900925-1901020 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT106255 NZ_CP029673:c1901105-1901048 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References