Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 214212..214392 Replicon chromosome
Accession NZ_AP024511
Organism Staphylococcus aureus isolate 2007-13

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag KJS82_RS01385 Protein ID WP_001801861.1
Coordinates 214297..214392 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 214212..214269 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KJS82_RS01355 209921..210055 + 135 WP_001791797.1 hypothetical protein -
KJS82_RS01360 210219..211775 + 1557 WP_000028669.1 type I restriction-modification system subunit M -
KJS82_RS01365 211768..212997 + 1230 WP_213607948.1 restriction endonuclease subunit S -
KJS82_RS01370 213539..213949 + 411 WP_001808705.1 IS21 family transposase -
KJS82_RS01375 213934..214095 + 162 Protein_238 transposase -
KJS82_RS01380 214073..214174 - 102 WP_001792025.1 hypothetical protein -
- 214212..214269 + 58 - - Antitoxin
KJS82_RS01385 214297..214392 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
KJS82_RS01390 214537..215549 + 1013 Protein_241 IS3 family transposase -
KJS82_RS01395 215747..216319 - 573 WP_000414216.1 hypothetical protein -
KJS82_RS01400 216420..216761 - 342 WP_000627540.1 DUF3969 family protein -
KJS82_RS01405 216802..217428 - 627 WP_000669024.1 hypothetical protein -
KJS82_RS01410 217503..218498 - 996 WP_000070642.1 DUF4352 domain-containing protein -
KJS82_RS01415 218579..219229 - 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - selk / hlgA / lukD 187381..219193 31812


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)


Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T38521 WP_001801861.1 NZ_AP024511:c214392-214297 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T38521 NZ_AP024511:c214392-214297 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT38521 NZ_AP024511:214212-214269 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References