Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1108555..1108735 Replicon chromosome
Accession NZ_CP029658
Organism Staphylococcus aureus strain AR_0467

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag CSC52_RS06145 Protein ID WP_001801861.1
Coordinates 1108640..1108735 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1108555..1108612 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSC52_RS06115 1104264..1104398 + 135 WP_001791797.1 hypothetical protein -
CSC52_RS06120 1104562..1106118 + 1557 WP_000028669.1 type I restriction-modification system subunit M -
CSC52_RS06125 1106111..1107340 + 1230 WP_000072627.1 restriction endonuclease subunit S -
CSC52_RS06130 1107792..1108286 + 495 Protein_1106 transposase -
CSC52_RS06135 1108277..1108438 + 162 Protein_1107 transposase -
CSC52_RS06140 1108416..1108517 - 102 WP_001792025.1 hypothetical protein -
- 1108555..1108612 + 58 - - Antitoxin
CSC52_RS06145 1108640..1108735 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
CSC52_RS06150 1108880..1109892 + 1013 Protein_1110 IS3 family transposase -
CSC52_RS06155 1110090..1110662 - 573 WP_000414216.1 hypothetical protein -
CSC52_RS06160 1110763..1111104 - 342 WP_000627540.1 DUF3969 family protein -
CSC52_RS06165 1111145..1111771 - 627 WP_000669024.1 hypothetical protein -
CSC52_RS06170 1111846..1112841 - 996 WP_000070642.1 DUF4352 domain-containing protein -
CSC52_RS06175 1112922..1113572 - 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - selk / hlgA / lukD 1072756..1114330 41574


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T106156 WP_001801861.1 NZ_CP029658:c1108735-1108640 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T106156 NZ_CP029658:c1108735-1108640 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT106156 NZ_CP029658:1108555-1108612 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References