Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 68197..68377 Replicon chromosome
Accession NZ_CP077858
Organism Staphylococcus aureus strain AC6

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag KU543_RS00510 Protein ID WP_001801861.1
Coordinates 68282..68377 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 68197..68254 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KU543_RS00480 63906..64040 + 135 WP_001791797.1 hypothetical protein -
KU543_RS00485 64204..65760 + 1557 WP_000028669.1 type I restriction-modification system subunit M -
KU543_RS00490 65753..66982 + 1230 WP_000072627.1 restriction endonuclease subunit S -
KU543_RS00495 67524..67934 + 411 WP_001808705.1 IS21 family transposase -
KU543_RS00500 67919..68080 + 162 Protein_60 transposase -
KU543_RS00505 68058..68159 - 102 WP_001792025.1 hypothetical protein -
- 68197..68254 + 58 - - Antitoxin
KU543_RS00510 68282..68377 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
KU543_RS00515 68522..69534 + 1013 Protein_63 IS3 family transposase -
KU543_RS00520 69732..70304 - 573 WP_000414216.1 hypothetical protein -
KU543_RS00525 70405..70746 - 342 WP_000627540.1 DUF3969 family protein -
KU543_RS00530 70787..71413 - 627 WP_000669024.1 hypothetical protein -
KU543_RS00535 71489..72484 - 996 WP_000070642.1 DUF4352 domain-containing protein -
KU543_RS00540 72565..73215 - 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - selk / hlgA / lukD 41365..73973 32608


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T208185 WP_001801861.1 NZ_CP077858:c68377-68282 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T208185 NZ_CP103589:c3709648-3709346 [Escherichia coli]
ATGGCTCAAAAGAAAAATATAAGGAGTTTTCGTGATGCCTGGTTGGCTGATTTTTTTGTCCATTCAACGCCACATCGAAA
GATCCCTGCTGAAATCCATACCACGTTATCACGAAAGTTGGACATCATTAATGCTGCCACTTCTCATCGGGATTTACGCT
CCCCTCCGGGGAACCGATACGAAGAGTTATCCGGGAAATTACAGGAATACTCCTCCATTAGAGTGAATAAACAGTACCGA
CTGATTTTTAAATGGGTTAATGGCAAGGCCGAAGAATTGTTTTTAGACCCACACAACTACTAA

Antitoxin


Download         Length: 58 bp

>AT208185 NZ_CP077858:68197-68254 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References