Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1996379..1996559 Replicon chromosome
Accession NZ_CP013953
Organism Staphylococcus aureus strain NCCP14558 isolate sequencing

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag ASL16_RS16080 Protein ID WP_001801861.1
Coordinates 1996379..1996474 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1996502..1996559 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ASL16_RS09870 1991542..1992192 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
ASL16_RS09875 1992273..1993268 + 996 WP_000070642.1 DUF4352 domain-containing protein -
ASL16_RS09880 1993343..1993969 + 627 WP_000669024.1 hypothetical protein -
ASL16_RS09885 1994010..1994351 + 342 WP_000627540.1 DUF3969 family protein -
ASL16_RS09890 1994452..1995024 + 573 WP_000414216.1 hypothetical protein -
ASL16_RS15655 1995222..1996234 - 1013 Protein_1912 IS3 family transposase -
ASL16_RS16080 1996379..1996474 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1996502..1996559 - 58 - - Antitoxin
ASL16_RS09910 1996597..1996698 + 102 WP_001792025.1 hypothetical protein -
ASL16_RS16085 1996676..1996837 - 162 Protein_1915 transposase -
ASL16_RS09915 1996828..1997322 - 495 Protein_1916 transposase -
ASL16_RS09920 1997774..1999003 - 1230 WP_000072627.1 restriction endonuclease subunit S -
ASL16_RS09925 1998996..2000552 - 1557 WP_000028669.1 type I restriction-modification system subunit M -
ASL16_RS09930 2000716..2000850 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 1990784..2025792 35008


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T59680 WP_001801861.1 NZ_CP013953:1996379-1996474 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T59680 NZ_CP013953:1996379-1996474 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT59680 NZ_CP013953:c1996559-1996502 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References