240695

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1833191..1833371 Replicon chromosome
Accession NZ_CP094857
Organism Staphylococcus aureus strain ATCC 29213

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag MTX75_RS08790 Protein ID WP_001801861.1
Coordinates 1833191..1833286 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1833314..1833371 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTX75_RS08760 1828354..1829004 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
MTX75_RS08765 1829085..1830080 + 996 WP_000070642.1 DUF4352 domain-containing protein -
MTX75_RS08770 1830155..1830781 + 627 WP_000669024.1 hypothetical protein -
MTX75_RS08775 1830822..1831163 + 342 WP_000627540.1 DUF3969 family protein -
MTX75_RS08780 1831264..1831836 + 573 WP_000414216.1 hypothetical protein -
MTX75_RS08785 1832034..1833046 - 1013 Protein_1727 IS3 family transposase -
MTX75_RS08790 1833191..1833286 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1833314..1833371 - 58 - - Antitoxin
MTX75_RS08795 1833409..1833510 + 102 WP_001792025.1 hypothetical protein -
MTX75_RS08800 1833488..1833649 - 162 Protein_1730 transposase -
MTX75_RS08805 1833634..1834044 - 411 WP_001808705.1 IS21 family transposase -
MTX75_RS08810 1834586..1835815 - 1230 WP_000072627.1 restriction endonuclease subunit S -
MTX75_RS08815 1835808..1837364 - 1557 WP_071621388.1 type I restriction-modification system subunit M -
MTX75_RS08820 1837528..1837662 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 1827596..1860202 32606


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T240695 WP_001801861.1 NZ_CP094857:1833191-1833286 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T240695 NZ_LT615377:c2092401-2092147 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGACGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 58 bp

>AT240695 NZ_CP094857:c1833371-1833314 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References