Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1891372..1891552 Replicon chromosome
Accession NZ_CP034008
Organism Staphylococcus aureus strain P1D5C2

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag EFD69_RS09105 Protein ID WP_001801861.1
Coordinates 1891372..1891467 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1891495..1891552 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EFD69_RS09075 1886535..1887185 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
EFD69_RS09080 1887266..1888261 + 996 WP_000070642.1 DUF4352 domain-containing protein -
EFD69_RS09085 1888336..1888962 + 627 WP_000669024.1 hypothetical protein -
EFD69_RS09090 1889003..1889344 + 342 WP_000627540.1 DUF3969 family protein -
EFD69_RS09095 1889445..1890017 + 573 WP_000414216.1 hypothetical protein -
EFD69_RS09100 1890215..1891227 - 1013 Protein_1774 IS3 family transposase -
EFD69_RS09105 1891372..1891467 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1891495..1891552 - 58 - - Antitoxin
EFD69_RS09110 1891590..1891691 + 102 WP_001792025.1 hypothetical protein -
EFD69_RS09115 1891669..1891830 - 162 Protein_1777 transposase -
EFD69_RS09120 1891821..1892315 - 495 Protein_1778 transposase -
EFD69_RS09125 1892767..1893996 - 1230 WP_000072627.1 restriction endonuclease subunit S -
EFD69_RS09130 1893989..1895545 - 1557 WP_064135920.1 type I restriction-modification system subunit M -
EFD69_RS09135 1895709..1895843 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 1885777..1920178 34401


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T114908 WP_001801861.1 NZ_CP034008:1891372-1891467 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T114908 NZ_CP034008:1891372-1891467 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT114908 NZ_CP034008:c1891552-1891495 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References