175172

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 173212..173392 Replicon chromosome
Accession NZ_CP062417
Organism Staphylococcus aureus strain NAS_AN_143

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag IF718_RS01080 Protein ID WP_001801861.1
Coordinates 173297..173392 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 173212..173269 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IF718_RS01050 168921..169055 + 135 WP_001791797.1 hypothetical protein -
IF718_RS01055 169219..170775 + 1557 WP_000028669.1 type I restriction-modification system subunit M -
IF718_RS01060 170768..171997 + 1230 WP_000072627.1 restriction endonuclease subunit S -
IF718_RS01065 172539..172949 + 411 WP_001808705.1 IS21 family transposase -
IF718_RS01070 172934..173095 + 162 Protein_175 transposase -
IF718_RS01075 173073..173174 - 102 WP_001792025.1 hypothetical protein -
- 173212..173269 + 58 - - Antitoxin
IF718_RS01080 173297..173392 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
IF718_RS01085 173537..174549 + 1013 Protein_178 IS3 family transposase -
IF718_RS01090 174747..175319 - 573 WP_000414216.1 hypothetical protein -
IF718_RS01095 175420..175761 - 342 WP_000627540.1 DUF3969 family protein -
IF718_RS01100 175802..176428 - 627 WP_000669024.1 hypothetical protein -
IF718_RS01105 176503..177498 - 996 WP_000070642.1 DUF4352 domain-containing protein -
IF718_RS01110 177579..178229 - 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - selk / hlgA / lukD 148311..178193 29882


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T175172 WP_001801861.1 NZ_CP062417:c173392-173297 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T175172 NZ_CP081791:2069704-2069807 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 58 bp

>AT175172 NZ_CP062417:173212-173269 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References