Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 2707291..2707471 Replicon chromosome
Accession NZ_CP042157
Organism Staphylococcus aureus strain B3-17D

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag FP481_RS13625 Protein ID WP_001801861.1
Coordinates 2707291..2707386 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2707414..2707471 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FP481_RS13595 2702454..2703104 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
FP481_RS13600 2703185..2704180 + 996 WP_000070642.1 DUF4352 domain-containing protein -
FP481_RS13605 2704255..2704881 + 627 WP_000669024.1 hypothetical protein -
FP481_RS13610 2704922..2705263 + 342 WP_000627540.1 DUF3969 family protein -
FP481_RS13615 2705364..2705936 + 573 WP_000414216.1 hypothetical protein -
FP481_RS13620 2706134..2707146 - 1013 Protein_2627 IS3 family transposase -
FP481_RS13625 2707291..2707386 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 2707414..2707471 - 58 - - Antitoxin
FP481_RS13630 2707509..2707610 + 102 WP_001792025.1 hypothetical protein -
FP481_RS13635 2707588..2707749 - 162 Protein_2630 transposase -
FP481_RS13640 2707740..2708234 - 495 Protein_2631 transposase -
FP481_RS13645 2708686..2709915 - 1230 WP_000072627.1 restriction endonuclease subunit S -
FP481_RS13650 2709908..2711464 - 1557 WP_000028669.1 type I restriction-modification system subunit M -
FP481_RS13655 2711628..2711762 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 2701696..2734302 32606


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T134915 WP_001801861.1 NZ_CP042157:2707291-2707386 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T134915 NZ_CP042157:2707291-2707386 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT134915 NZ_CP042157:c2707471-2707414 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References