79872

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1184590..1184770 Replicon chromosome
Accession NZ_CP022893
Organism Staphylococcus aureus strain 61

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag CGP89_RS06375 Protein ID WP_001801861.1
Coordinates 1184675..1184770 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1184590..1184647 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CGP89_RS06345 1180299..1180433 + 135 WP_001791797.1 hypothetical protein -
CGP89_RS06350 1180597..1182153 + 1557 WP_000028669.1 type I restriction-modification system subunit M -
CGP89_RS06355 1182146..1183375 + 1230 WP_000072627.1 restriction endonuclease subunit S -
CGP89_RS06360 1183827..1184321 + 495 Protein_1142 transposase -
CGP89_RS06365 1184312..1184473 + 162 Protein_1143 transposase -
CGP89_RS06370 1184451..1184552 - 102 WP_001792025.1 hypothetical protein -
- 1184590..1184647 + 58 - - Antitoxin
CGP89_RS06375 1184675..1184770 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
CGP89_RS06380 1184915..1185927 + 1013 Protein_1146 IS3 family transposase -
CGP89_RS06385 1186125..1186697 - 573 WP_000414216.1 hypothetical protein -
CGP89_RS06390 1186798..1187139 - 342 WP_000627540.1 DUF3969 family protein -
CGP89_RS06395 1187180..1187806 - 627 WP_000669024.1 hypothetical protein -
CGP89_RS06400 1187881..1188876 - 996 WP_000070642.1 DUF4352 domain-containing protein -
CGP89_RS06405 1188957..1189607 - 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - selk / hlgA / lukD 1155093..1189571 34478


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T79872 WP_001801861.1 NZ_CP022893:c1184770-1184675 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T79872 NZ_CP022893:c1184770-1184675 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT79872 NZ_CP022893:1184590-1184647 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References