93228

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1831504..1831684 Replicon chromosome
Accession NZ_CP026079
Organism Staphylococcus aureus strain FDAARGOS_9

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag RK67_RS14575 Protein ID WP_001801861.1
Coordinates 1831589..1831684 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1831504..1831561 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RK67_RS09675 1827213..1827347 + 135 WP_001791797.1 hypothetical protein -
RK67_RS09680 1827511..1829067 + 1557 WP_000028669.1 type I restriction-modification system subunit M -
RK67_RS09685 1829060..1830289 + 1230 WP_000072627.1 restriction endonuclease subunit S -
RK67_RS09690 1830741..1831235 + 495 Protein_1772 transposase -
RK67_RS09695 1831226..1831387 + 162 Protein_1773 transposase -
RK67_RS09700 1831365..1831466 - 102 WP_001792025.1 hypothetical protein -
- 1831504..1831561 + 58 - - Antitoxin
RK67_RS14575 1831589..1831684 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
RK67_RS09705 1831829..1832841 + 1013 Protein_1776 IS3 family transposase -
RK67_RS09710 1833039..1833611 - 573 WP_000414216.1 hypothetical protein -
RK67_RS09715 1833712..1834053 - 342 WP_000627540.1 DUF3969 family protein -
RK67_RS09720 1834094..1834720 - 627 WP_000669024.1 hypothetical protein -
RK67_RS09725 1834795..1835790 - 996 WP_000070642.1 DUF4352 domain-containing protein -
RK67_RS09730 1835871..1836521 - 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - selk / hlgA / lukD 1804672..1837279 32607


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T93228 WP_001801861.1 NZ_CP026079:c1831684-1831589 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T93228 NZ_CP026079:c1831684-1831589 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT93228 NZ_CP026079:1831504-1831561 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References