104771

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1859350..1859530 Replicon chromosome
Accession NZ_CP029082
Organism Staphylococcus aureus strain AR465

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag CSC50_RS10120 Protein ID WP_001801861.1
Coordinates 1859435..1859530 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1859350..1859407 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSC50_RS10090 1855059..1855193 + 135 WP_001791797.1 hypothetical protein -
CSC50_RS10095 1855357..1856913 + 1557 WP_000028669.1 type I restriction-modification system subunit M -
CSC50_RS10100 1856906..1858135 + 1230 WP_000072627.1 restriction endonuclease subunit S -
CSC50_RS10105 1858587..1859081 + 495 Protein_1815 transposase -
CSC50_RS10110 1859072..1859233 + 162 Protein_1816 transposase -
CSC50_RS10115 1859211..1859312 - 102 WP_001792025.1 hypothetical protein -
- 1859350..1859407 + 58 - - Antitoxin
CSC50_RS10120 1859435..1859530 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
CSC50_RS10125 1859675..1860687 + 1013 Protein_1819 IS3 family transposase -
CSC50_RS10130 1860885..1861457 - 573 WP_000414216.1 hypothetical protein -
CSC50_RS10135 1861558..1861899 - 342 WP_000627540.1 DUF3969 family protein -
CSC50_RS10140 1861940..1862566 - 627 WP_000669024.1 hypothetical protein -
CSC50_RS10145 1862641..1863636 - 996 WP_000070642.1 DUF4352 domain-containing protein -
CSC50_RS10150 1863717..1864367 - 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - selk / hlgA / lukD 1834449..1866762 32313


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T104771 WP_001801861.1 NZ_CP029082:c1859530-1859435 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T104771 NZ_CP029082:c1859530-1859435 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT104771 NZ_CP029082:1859350-1859407 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References