Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 580215..580395 Replicon chromosome
Accession NZ_CP077855
Organism Staphylococcus aureus strain L6

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag KU520_RS03270 Protein ID WP_001801861.1
Coordinates 580300..580395 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 580215..580272 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KU520_RS03240 575924..576058 + 135 WP_001791797.1 hypothetical protein -
KU520_RS03245 576222..577778 + 1557 WP_000028669.1 type I restriction-modification system subunit M -
KU520_RS03250 577771..579000 + 1230 WP_000072627.1 restriction endonuclease subunit S -
KU520_RS03255 579542..579952 + 411 WP_001808705.1 IS21 family transposase -
KU520_RS03260 579937..580098 + 162 Protein_599 transposase -
KU520_RS03265 580076..580177 - 102 WP_001792025.1 hypothetical protein -
- 580215..580272 + 58 - - Antitoxin
KU520_RS03270 580300..580395 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
KU520_RS03275 580540..581552 + 1013 Protein_602 IS3 family transposase -
KU520_RS03280 581750..582322 - 573 WP_000414216.1 hypothetical protein -
KU520_RS03285 582423..582764 - 342 WP_000627540.1 DUF3969 family protein -
KU520_RS03290 582805..583431 - 627 WP_000669024.1 hypothetical protein -
KU520_RS03295 583507..584502 - 996 WP_000070642.1 DUF4352 domain-containing protein -
KU520_RS03300 584583..585233 - 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - selk / hlgA / lukD 553382..585991 32609


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T208141 WP_001801861.1 NZ_CP077855:c580395-580300 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T208141 NZ_CP103579:3997830-3998048 [Klebsiella pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACTTCTGTCTGGAAATTTATCCGCTAA

Antitoxin


Download         Length: 58 bp

>AT208141 NZ_CP077855:580215-580272 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References