Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1940775..1940955 Replicon chromosome
Accession NZ_CP029657
Organism Staphylococcus aureus strain AR_0468

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag CSC53_RS10015 Protein ID WP_001801861.1
Coordinates 1940775..1940870 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1940898..1940955 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSC53_RS09985 1935938..1936588 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
CSC53_RS09990 1936669..1937664 + 996 WP_000070642.1 DUF4352 domain-containing protein -
CSC53_RS09995 1937739..1938365 + 627 WP_000669024.1 hypothetical protein -
CSC53_RS10000 1938406..1938747 + 342 WP_000627540.1 DUF3969 family protein -
CSC53_RS10005 1938848..1939420 + 573 WP_000414216.1 hypothetical protein -
CSC53_RS10010 1939618..1940630 - 1013 Protein_1851 IS3 family transposase -
CSC53_RS10015 1940775..1940870 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1940898..1940955 - 58 - - Antitoxin
CSC53_RS10020 1940993..1941094 + 102 WP_001792025.1 hypothetical protein -
CSC53_RS10025 1941072..1941233 - 162 Protein_1854 transposase -
CSC53_RS10030 1941224..1941718 - 495 Protein_1855 transposase -
CSC53_RS10035 1942170..1943399 - 1230 WP_000072627.1 restriction endonuclease subunit S -
CSC53_RS10040 1943392..1944948 - 1557 WP_000028669.1 type I restriction-modification system subunit M -
CSC53_RS10045 1945112..1945246 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 1935180..1970458 35278


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T106128 WP_001801861.1 NZ_CP029657:1940775-1940870 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T106128 NZ_CP029657:1940775-1940870 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT106128 NZ_CP029657:c1940955-1940898 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References