22115

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1979658..1979838 Replicon chromosome
Accession NC_009487
Organism Staphylococcus aureus subsp. aureus JH9

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag SAURJH9_RS15870 Protein ID WP_001801861.1
Coordinates 1979658..1979753 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1979781..1979838 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAURJH9_RS09865 1974821..1975471 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
SAURJH9_RS09870 1975552..1976547 + 996 WP_000070642.1 DUF4352 domain-containing protein -
SAURJH9_RS09875 1976622..1977248 + 627 WP_000669024.1 hypothetical protein -
SAURJH9_RS09880 1977289..1977630 + 342 WP_000627540.1 DUF3969 family protein -
SAURJH9_RS09885 1977731..1978303 + 573 WP_000414216.1 hypothetical protein -
SAURJH9_RS15520 1978501..1979513 - 1013 Protein_1909 IS3 family transposase -
SAURJH9_RS15870 1979658..1979753 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1979781..1979838 - 58 - - Antitoxin
SAURJH9_RS09905 1979876..1979977 + 102 WP_001792025.1 hypothetical protein -
SAURJH9_RS15875 1979955..1980116 - 162 Protein_1912 transposase -
SAURJH9_RS09910 1980107..1980601 - 495 Protein_1913 transposase -
SAURJH9_RS09915 1981053..1982282 - 1230 WP_000072627.1 restriction endonuclease subunit S -
SAURJH9_RS09920 1982275..1983831 - 1557 WP_000028669.1 type I restriction-modification system subunit M -
SAURJH9_RS09925 1983995..1984129 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 1974062..2005794 31732


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T22115 WP_001801861.1 NC_009487:1979658-1979753 [Staphylococcus aureus subsp. aureus JH9]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T22115 NC_009487:1979658-1979753 [Staphylococcus aureus subsp. aureus JH9]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT22115 NC_009487:c1979838-1979781 [Staphylococcus aureus subsp. aureus JH9]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References