148407

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 174454..174634 Replicon chromosome
Accession NZ_CP047863
Organism Staphylococcus aureus strain UP_1106

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag E3S63_RS01085 Protein ID WP_001801861.1
Coordinates 174539..174634 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 174454..174511 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3S63_RS01055 170163..170297 + 135 WP_001791797.1 hypothetical protein -
E3S63_RS01060 170461..172017 + 1557 WP_000028669.1 type I restriction-modification system subunit M -
E3S63_RS01065 172010..173239 + 1230 WP_000072627.1 restriction endonuclease subunit S -
E3S63_RS01070 173691..174185 + 495 Protein_175 transposase -
E3S63_RS01075 174176..174337 + 162 Protein_176 transposase -
E3S63_RS01080 174315..174416 - 102 WP_001792025.1 hypothetical protein -
- 174454..174511 + 58 - - Antitoxin
E3S63_RS01085 174539..174634 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
E3S63_RS01090 174779..175791 + 1013 Protein_179 IS3 family transposase -
E3S63_RS01095 175989..176561 - 573 WP_000414216.1 hypothetical protein -
E3S63_RS01100 176662..177003 - 342 WP_000627540.1 DUF3969 family protein -
E3S63_RS01105 177044..177670 - 627 WP_000669024.1 hypothetical protein -
E3S63_RS01110 177745..178740 - 996 WP_000070642.1 DUF4352 domain-containing protein -
E3S63_RS01115 178821..179471 - 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - selk / hlgA / lukD 147621..179435 31814


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T148407 WP_001801861.1 NZ_CP047863:c174634-174539 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T148407 NZ_CP063515:950027-950401 [Escherichia coli]
ATGAAAACATTACCTGTATTACCCGGGCAGGCGGCCAGTTCTCGCCCGTCTCCTGTTGAAATCTGGCAGATACTGCTGTC
CCGACTACTGGACCAGCACTATGGCCTCACACTGAATGACACACCTTTTGCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCAGTGAACTTTCTCGTTGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCGCTCTCAGTTAATAAACAGCATCGATATCCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGTATCCGGAGGCGAAATGA

Antitoxin


Download         Length: 58 bp

>AT148407 NZ_CP047863:174454-174511 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References