Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 174453..174633 Replicon chromosome
Accession NZ_CP047856
Organism Staphylococcus aureus strain UP_1435

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag E3S66_RS01085 Protein ID WP_001801861.1
Coordinates 174538..174633 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 174453..174510 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E3S66_RS01055 170162..170296 + 135 WP_001791797.1 hypothetical protein -
E3S66_RS01060 170460..172016 + 1557 WP_000028669.1 type I restriction-modification system subunit M -
E3S66_RS01065 172009..173238 + 1230 WP_000072627.1 restriction endonuclease subunit S -
E3S66_RS01070 173690..174184 + 495 Protein_176 transposase -
E3S66_RS01075 174175..174336 + 162 Protein_177 transposase -
E3S66_RS01080 174314..174415 - 102 WP_001792025.1 hypothetical protein -
- 174453..174510 + 58 - - Antitoxin
E3S66_RS01085 174538..174633 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
E3S66_RS01090 174778..175790 + 1013 Protein_180 IS3 family transposase -
E3S66_RS01095 175988..176560 - 573 WP_000414216.1 hypothetical protein -
E3S66_RS01100 176661..177002 - 342 WP_000627540.1 DUF3969 family protein -
E3S66_RS01105 177043..177669 - 627 WP_000669024.1 hypothetical protein -
E3S66_RS01110 177744..178739 - 996 WP_160176654.1 DUF4352 domain-containing protein -
E3S66_RS01115 178820..179470 - 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - selk / hlgA / lukD 147621..179434 31813


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T148352 WP_001801861.1 NZ_CP047856:c174633-174538 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T148352 NZ_CP063499:4214526-4214822 [Escherichia coli]
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCACTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA

Antitoxin


Download         Length: 58 bp

>AT148352 NZ_CP047856:174453-174510 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References