Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1933741..1933921 Replicon chromosome
Accession NZ_CP029675
Organism Staphylococcus aureus strain AR_0219

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag CSB75_RS09965 Protein ID WP_001801861.1
Coordinates 1933741..1933836 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1933864..1933921 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSB75_RS09935 1928904..1929554 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
CSB75_RS09940 1929635..1930630 + 996 WP_000070642.1 DUF4352 domain-containing protein -
CSB75_RS09945 1930705..1931331 + 627 WP_000669024.1 hypothetical protein -
CSB75_RS09950 1931372..1931713 + 342 WP_000627540.1 DUF3969 family protein -
CSB75_RS09955 1931814..1932386 + 573 WP_000414216.1 hypothetical protein -
CSB75_RS09960 1932584..1933596 - 1013 Protein_1839 IS3 family transposase -
CSB75_RS09965 1933741..1933836 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1933864..1933921 - 58 - - Antitoxin
CSB75_RS09970 1933959..1934060 + 102 WP_001792025.1 hypothetical protein -
CSB75_RS09975 1934038..1934199 - 162 Protein_1842 transposase -
CSB75_RS09980 1934190..1934684 - 495 Protein_1843 transposase -
CSB75_RS09985 1935136..1936365 - 1230 WP_000072626.1 restriction endonuclease subunit S -
CSB75_RS09990 1936358..1937914 - 1557 WP_000028669.1 type I restriction-modification system subunit M -
CSB75_RS09995 1938078..1938212 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 1928146..1960753 32607


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T106271 WP_001801861.1 NZ_CP029675:1933741-1933836 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T106271 NZ_CP029675:1933741-1933836 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT106271 NZ_CP029675:c1933921-1933864 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References