Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 173130..173310 Replicon chromosome
Accession NZ_CP062409
Organism Staphylococcus aureus strain NAS_AN_239

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag IF734_RS01080 Protein ID WP_001801861.1
Coordinates 173215..173310 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 173130..173187 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IF734_RS01050 168839..168973 + 135 WP_001791797.1 hypothetical protein -
IF734_RS01055 169137..170693 + 1557 WP_000028669.1 type I restriction-modification system subunit M -
IF734_RS01060 170686..171915 + 1230 WP_000072627.1 restriction endonuclease subunit S -
IF734_RS01065 172457..172867 + 411 WP_001808705.1 IS21 family transposase -
IF734_RS01070 172852..173013 + 162 Protein_175 transposase -
IF734_RS01075 172991..173092 - 102 WP_001792025.1 hypothetical protein -
- 173130..173187 + 58 - - Antitoxin
IF734_RS01080 173215..173310 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
IF734_RS01085 173455..174467 + 1013 Protein_178 IS3 family transposase -
IF734_RS01090 174665..175237 - 573 WP_000414216.1 hypothetical protein -
IF734_RS01095 175338..175679 - 342 WP_000627540.1 DUF3969 family protein -
IF734_RS01100 175720..176346 - 627 WP_000669024.1 hypothetical protein -
IF734_RS01105 176421..177416 - 996 WP_000070642.1 DUF4352 domain-containing protein -
IF734_RS01110 177497..178147 - 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - selk / hlgA / lukD 146297..178905 32608


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T175025 WP_001801861.1 NZ_CP062409:c173310-173215 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T175025 NZ_CP081742:c661625-661161 [Escherichia coli]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCCGCCACAAAGTTATTGGCGGTAGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGATGCTGGTCGTTATCGTCTCTTCTTTCGTTATAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACTCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAACCCTCACCCGAGAAACAGAAGAAACCCATTGA

Antitoxin


Download         Length: 58 bp

>AT175025 NZ_CP062409:173130-173187 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References